Hydrochloric Acid → HCID 68154199, compound

Participants

Reaction Steps

24 mg (1.3 mmol) lithium hydroxide in 1.0 ml of water were added to 0.55 g (1.1 mmol) (2R)-tert-butyl-2-(cycloheptylmethyl)-5-(3,5-difluorophenyl)-4-(2-methoxy-2-oxoethyl)-3-oxopiperazine-1-carboxylate (isomer 4.1.1) in 5 ml THF. After 2 h at RT the mixture was neutralised with 0.1 M hydrochloric acid solution. The reaction mixture was evaporated to dryness by rotary evaporation.

Provenance & Evidence