HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminocyclohexanecarboxylic acid → Methyl 1-aminocyclohexane-1-carboxylate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminocyclohexanecarboxylic acid | HCID 1366 | — |
| Reactant | (RS)-1-(3,5-Difluorophenyl)ethylamine | HCID 2783196 | — |
| Reactant | Methyl 1-amino-1-cyclopentanecarboxylate, HCl | HCID 11513856 | — |
| Product | Methyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 22645079 | — |
Reaction Steps
Essentially following the procedures described in Intermediate 1 for methyl 1-aminocyclopentanecarboxylate hydrochloride, but using 1-aminocyclohexanecarboxylic acid in place of 1-aminocyclopentanecarboxylic acid, the title compound was obtained. MS: m/z=158 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765759B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-8cb5bc9917154894ae223626838053a8 |
| Source note | uspto-grants-2014_07 |