HCID 44540226, compound → HCID 44540225, compound

Participants

Reaction Steps

N-[6-(1H-Indol-4-yl)-1H-indazol-4-yl]-3-(1-methylethenyl)-2-pyridinecarboxamide (166 mg, 0.42 mmol, prepared as described in Example 62) was dissolved in ethanol and hydrogenated at 25° C. on the H-cube using a 5% palladium on carbon catalyst. The mixture was passed through the flow reactor twice then the catalyst was replaced before the mixture was passed through another two times. The solvent was removed in a stream of nitrogen to give a pale yellow oil. This was purified by mass-directed automated preparative HPLC (Method B) to give the title compound (17 mg) as a white solid.

Provenance & Evidence