Phosphorus oxybromide → HCID 86691860, compound

Participants

Reaction Steps

To a solution of 51-1 (150 mg, 0.44 mmol) in DCM (2 mL) at 0° C. was added phosphorus oxybromide (126 mg, 0.46 mmol). After 4 hours, the reaction was diluted with EtOAc, and washed with water, saturated aqueous sodium bicarbonate and brine. The organic layer was dried over Na2SO4, filtered and concentrated to give product as a white foam. MS (M+H)+: observed=402.0/404.0, calculated=402.3/404.3.

Provenance & Evidence