Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Solifenacin | HCID 154059 | — |
| Reactant | Maleic Acid | HCID 444266 | — |
| Solvent | Isopropyl Acetate | HCID 7915 | — |
| Product | Solifenacin Maleate | HCID 86691620 | — |
Reaction Steps
6 g of solifenacin base from example 1 was dissolved in 60 ml of isopropyl acetate; 1.92 g of maleic acid was added and the mixture was heated to 45° C. for 15 minutes. The mixture is kept at room temperature overnight. In these conditions a colorless oil is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08765785B2 |
|---|
| Source dataset | uspto-grants-2014_07 |
|---|
| ORD ID | ord-75636614ca914215b7c4da893fa77b56 |
|---|
| Source note | uspto-grants-2014_07 |
|---|
