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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1616268Generated: November 2, 2026

1,3-Dibromopropane → 2-(Butyloxy)-8-(methyloxy)-9-[3-(1-pyrrolidinyl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1616268

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DibromopropaneHCID 8001—
ReactantPyrrolidineHCID 31268—
Reactant9-[3-(1-Azetidinyl)propyl]-2-(butyloxy)-8-(methyloxy)-9H-purin-6-amineHCID 59252600—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-[3-(1-pyrrolidinyl)propyl]-9H-purin-6-amineHCID 59252595—

Reaction Steps

Prepared similarly to Intermediate 20 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate, 1,3-dibromopropane and pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765772B2
Source datasetuspto-grants-2014_07
ORD IDord-bb79f551176c4bc380b524b35d8aebeb
Source noteuspto-grants-2014_07