HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-chlorobutane → 9-(4-Chlorobutyl)-2-(cyclopentyloxy)-8-(methyloxy)-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-chlorobutane | HCID 81364 | — |
| Reactant | 9-(4-Chlorobutyl)-8-(methyloxy)-2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amine | HCID 59252648 | — |
| Reactant | HCID 178494007 | HCID 178494007 | — |
| Product | 9-(4-Chlorobutyl)-2-(cyclopentyloxy)-8-(methyloxy)-9H-purin-6-amine | HCID 59252590 | — |
Reaction Steps
Prepared similarly to Intermediate 44 from 2-(cyclopentyloxy)-8-(methyloxy) -1H-purin-6-amine trifluoroacetate and 1-bromo-4-chlorobutane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765772B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-f095fd52ae1444bf8c75319b2a130e80 |
| Source note | uspto-grants-2014_07 |