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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1616306Generated: October 31, 2026

1-Bromo-4-chlorobutane → 9-(4-chlorobutyl)-2-(cyclohexyloxy)-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/1616306

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-chlorobutaneHCID 81364—
Reactant9-(4-Chlorobutyl)-8-(methyloxy)-2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amineHCID 59252648—
ReactantHCID 178494008HCID 178494008—
Product9-(4-chlorobutyl)-2-(cyclohexyloxy)-8-(methyloxy)-9H-purin-6-amineHCID 59252651—

Reaction Steps

Prepared similarly to Intermediate 44 from 2-(cyclohexyloxy)-8-(methyloxy) -1H-purin-6-amine trifluoroacetate and 1-bromo-4-chlorobutane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765772B2
Source datasetuspto-grants-2014_07
ORD IDord-81c561d1f38f4a0eb180126f8d0e42be
Source noteuspto-grants-2014_07