HCID 59252558, compound → HCID 59252581, compound

HRID 1616313Notes

Reaction equation

HRID 1616313 reaction equation
[Br:1][C:2]1[N:3]([CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][O:19]2)[C:4]2[C:9]([N:10]=1)=[C:8]([NH2:11])[N:7]=[C:6]([NH:12][C@H:13]([CH3:17])[CH2:14][CH2:15][CH3:16])[N:5]=2.C[C@H](NC1N=C2C(N=CN2C2CCCCO2)=C(N)N=1)CCC>>[Br:1][C:2]1[N:3]([CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][O:19]2)[C:4]2[C:9]([N:10]=1)=[C:8]([NH2:11])[N:7]=[C:6]([NH:12][C@@H:13]([CH3:17])[CH2:14][CH2:15][CH3:16])[N:5]=2

Participants

3

Reactant 2

HCID 59252558HCID 59252558, compoundHCID 59252576HCID 59252576, compound

Product 1

HCID 59252581HCID 59252581, compound

Procedure

Prepared similarly to Intermediate 71 from N2-[(1S)-1-methylbutyl]-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2,6-diamine.

Sources & evidence

ORD record
ord-2dddd97ddd204e018a9ad78ed51be4a4
Source dataset
uspto-grants-2014_07
Patent number
US08765772B2

Reaction notes

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