HCID 59252556, compound → HCID 178448280, compound

HRID 1616315Notes

Reaction equation

HRID 1616315 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH3:8][C@@H:9]([NH:13][C:14]1[NH:22][C:21]2[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]=2)=[C:16]([NH2:25])[N:15]=1)[CH2:10][CH2:11][CH3:12].C[C@H](NC1N=C2C(N=C(OC)N2C2CCCCO2)=C(N)N=1)CCC>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH3:8][C@H:9]([NH:13][C:14]1[NH:22][C:21]2[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]=2)=[C:16]([NH2:25])[N:15]=1)[CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 59252556HCID 59252556, compoundHCID 178448279HCID 178448279, compound

Product 1

HCID 178448280HCID 178448280, compound

Procedure

Prepared similarly to Intermediate 73 from N2-[(1S)-1-methylbutyl]-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2,6-diamine.

Sources & evidence

ORD record
ord-230ed41452d74ebfadd919a3abf027cb
Source dataset
uspto-grants-2014_07
Patent number
US08765772B2

Reaction notes

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