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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1616326Generated: October 31, 2026

Azepane → 6-Amino-9-[5-(hexahydro-1H-azepin-1-yl)pentyl]-2-{[(1S)-1-methylbutyl]oxy}-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/1616326

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzepaneHCID 8119—
Reactant1-Bromo-5-chloropentaneHCID 96070—
ReactantHCID 178448285HCID 178448285—
Product6-Amino-9-[5-(hexahydro-1H-azepin-1-yl)pentyl]-2-{[(1S)-1-methylbutyl]oxy}-7,9-dihydro-8H-purin-8-oneHCID 44816737—

Reaction Steps

Prepared similarly to Example 19 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate, 1-bromo-5-chloropentane and hexahydro-1H-azepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765772B2
Source datasetuspto-grants-2014_07
ORD IDord-04b944ee49f246d885a400b643db5ce3
Source noteuspto-grants-2014_07