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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1616327Generated: October 31, 2026

Piperidine → 6-Amino-2-{[(1S)-1-methylpropyl]oxy}-9-[4-(1-piperidinyl)butyl]-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/1616327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant9-(4-Chlorobutyl)-8-(methyloxy)-2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amineHCID 59252648—
Product6-Amino-2-{[(1S)-1-methylpropyl]oxy}-9-[4-(1-piperidinyl)butyl]-7,9-dihydro-8H-purin-8-oneHCID 59252591—

Reaction Steps

Prepared similarly to Example 29 from 9-(4-chlorobutyl)-8-(methyloxy) -2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amine and piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765772B2
Source datasetuspto-grants-2014_07
ORD IDord-30429290ff7a46479b31b99bf55026ee
Source noteuspto-grants-2014_07