HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-Ethoxycarbonimidoylheptanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 7-Cyanoheptanoic acid ethyl ester | HCID 86208322 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 7-Ethoxycarbonimidoylheptanoic acid ethyl ester | HCID 86034724 | 117.7% |
Reaction Steps
Bubble hydrogen chloride gas into a solution of 7-cyanoheptanoic acid ethyl ester (3.7 g, 20.0 mmol) in ethanol (24 mL, 40 mmol) and diethyl ether (100 mL) at 0° C. for 15 minutes. Remove the solvent under reduced pressure to provide 7-ethoxycarbonimidoylheptanoic acid ethyl ester (5.4 g, >99%), which is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765796B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-995482e9b2a445b4bd79e9661c7f5012 |
| Source note | uspto-grants-2014_07 |