Ethanol → HCID 58497730, compound

Participants

Reaction Conditions

Reaction Steps

SOCl2 (5 mL) is added dropwise to a suspension of 4-[(2R,6S)-10-hydroxy-6,11,11-trimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocine-3-carbonyl]-cyclohexanecarboxylic acid (100 mg) in ethanol (5 mL) cooled to −20° C. Then, the cooling bath is removed and the resulting mixture is stirred at ambient temperature overnight. The solution is concentrated under reduced pressure and the residue is triturated with acetone and dried.

Provenance & Evidence