HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Fluorobenzenethiol → 7-[(3-Fluorophenyl)sulfonyl]-2'-methyl-3,4,4',5'-tetrahydro-2H-spiro[1-benzofuro[2,3-c]pyridine-1,3'-furan]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Fluorobenzenethiol | HCID 75710 | — |
| Reactant | 7-[(3-fluorophenyl)sulfonyl]-3,4,5',6'-tetrahydro-2H,4'H-spiro[1-benzofuro[2,3-c]pyridine-1,3'-pyran] | HCID 53327611 | — |
| Reactant | 7-Iodo-2'-methyl-3,4,4',5'-tetrahydro-2H-spiro[1-benzofuro[2,3-c]pyridine-1,3'-furan] | HCID 67324945 | — |
| Product | 7-[(3-Fluorophenyl)sulfonyl]-2'-methyl-3,4,4',5'-tetrahydro-2H-spiro[1-benzofuro[2,3-c]pyridine-1,3'-furan] | HCID 53327614 | — |
Reaction Steps
Prepared as described for 7-[(3-fluorophenyl)sulfonyl]-3,4,5′,6′-tetrahydro-2H,4′H-spiro[1-benzofuro[2,3-c]pyridine-1,3′-pyran] (Example 22) starting from 3-fluorobenzenethiol and 7-iodo-2′-methyl-3,4,4′,5′-tetrahydro-2H-spiro[1-benzofuro[2,3-c]pyridine-1,3′-furan].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765779B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-141888000b1d404995dd66c93126337c |
| Source note | uspto-grants-2014_07 |