Isobutyric anhydride → HCID 67324731, compound

HRID 1616882Notes

Reaction equation

HRID 1616882 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([S:8]([C:11]2[CH:16]=[CH:15][C:14]3[C:17]4[CH2:22][CH2:21][NH:20][C:19]([CH2:24][NH:25][C:26](=[O:30])[CH:27](C)C)([CH3:23])[C:18]=4[O:31][C:13]=3[CH:12]=2)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.CC(OCC1C2C(=CC=CC=2)C(COC(C)=O)=C2C=1C=CC=C2)=O.CC(C)C(OC(=O)C(C)C)=O>>[F:1][C:2]1[CH:3]=[C:4]([S:8]([C:11]2[CH:16]=[CH:15][C:14]3[C:17]4[CH2:22][CH2:21][NH:20][C:19]([CH2:24][NH:25][C:26](=[O:30])[CH3:27])([CH3:23])[C:18]=4[O:31][C:13]=3[CH:12]=2)(=[O:9])=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 7346Isobutyric anhydrideHCID 613145Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl esterHCID 53326985HCID 53326985, compound

Product 1

HCID 67324731HCID 67324731, compound

Procedure

Prepared as described for N-[7-(3-Fluoro-benzenesulfonyl)-1-methyl-1,2,3,4-tetrahydro-benzofuro[2,3-c]pyridin-1-ylmethyl]isobutyramide using acetic anhhydride instead of 2-methylpropanoic anhydride. mp 140-155° C. dec.; MS m/z 417 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-bceb00cb30354353bb22e853b32da199
Source dataset
uspto-grants-2014_07
Patent number
US08765779B2

Reaction notes

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