HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetamide → N-(2-{6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}ethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetamide | HCID 178 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1,3-Dioxolane-2-ethylamine | HCID 79827 | — |
| Reactant | N-({6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)acetamide | HCID 67325542 | — |
| Reactant | N-[1,3]dioxolan-2-yl-ethylamine | HCID 68794696 | — |
| Reactant | Tert-butyl (2-{5-[(3-fluorophenyl)sulfonyl]-1-benzofuran-3-yl}ethyl)carbamate | HCID 86673691 | — |
| Product | N-(2-{6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}ethyl)acetamide | HCID 67325386 | — |
Reaction Steps
Prepared as described for N-({6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)acetamide using tert-butyl (2-{5-[(3-fluorophenyl)sulfonyl]-1-benzofuran-3-yl}ethyl)carbamate and N-[1,3]dioxolan-2-yl-ethylamine)-acetamide, which was prepared from 2-[1,3]dioxolan-2-yl-ethylamine and acetic anhydride. MS m/z 417 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765779B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-21f1e53bbd7a4c92b801bb53a16ccd1b |
| Source note | uspto-grants-2014_07 |