HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetamide → N-({6-[(3-Fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)-N-methylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetamide | HCID 178 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1,3-Dioxolane-2-methanamine, N-methyl- | HCID 541754 | — |
| Reactant | N-({6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)acetamide | HCID 67325542 | — |
| Reactant | Tert-butyl (2-{5-[(3-fluorophenyl)sulfonyl]-1-benzofuran-3-yl}ethyl)carbamate | HCID 86673691 | — |
| Product | N-({6-[(3-Fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)-N-methylacetamide | HCID 67326062 | — |
Reaction Steps
Prepared as described for N-({6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridin-1-yl}methyl)acetamide using tert-butyl (2-{5-[(3-fluorophenyl)sulfonyl]-1-benzofuran-3-yl}ethyl)carbamate and N-[1,3]dioxolan-2-ylmethyl-methyl)-acetamide, which was prepared from [1,3]dioxolan-2-ylmethyl-methyl-amine and acetic anhydride. MS m/z 417 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765779B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d85d2ab695b14c4abb77e0d6c565f9b3 |
| Source note | uspto-grants-2014_07 |