3-(Benzyloxy)benzene-1-thiol → 7-(3-benzyloxy-benzenesulfonyl)-3,4-dihydro-1H-benzofuro[2,3-c]pyridine-2-carboxylic acid tert-butyl ester

HRID 1616893Notes

Reaction equation

HRID 1616893 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]2[C:14]3[CH:20]=[CH:19][C:18]([S:21]([C:24]4[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH2:31][C:32]5[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=5)[CH:25]=4)(=[O:23])=[O:22])=[CH:17][C:15]=3[O:16][CH:10]2[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].IC1C=CC2C3CCNCC=3OC=2C=1.C(OC1C=C(S)C=CC=1)C1C=CC=CC=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11]2[C:14]3[CH:20]=[CH:19][C:18]([S:21]([C:24]4[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH2:31][C:32]5[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=5)[CH:25]=4)(=[O:23])=[O:22])=[CH:17][C:15]=3[O:16][C:10]=2[CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 249006013-(Benzyloxy)benzene-1-thiolHCID 673248767-Iodo-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridineHCID 67325213HCID 67325213, compound

Product 1

HCID 673238427-(3-benzyloxy-benzenesulfonyl)-3,4-dihydro-1H-benzofuro[2,3-c]pyridine-2-carboxylic acid tert-butyl ester

Procedure

Prepared as described for 7-(3-benzyloxy-benzenesulfonyl)-3,4,4a,9a-tetrahydro-1H-benzo[4,5]furo[2,3-c]pyridine-2-carboxylic acid tert-butyl ester using 7-iodo-1,2,3,4-tetrahydro-benzo[4,5]furo[2,3-c]pyridine and 3-benzyloxy-thiophenol

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8e8a0d8bb6d34931b276591b3d3b4b99
Source dataset
uspto-grants-2014_07
Patent number
US08765779B2

Reaction notes

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