HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-methoxyphenol → Tert-butyl 6-hydroxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-methoxyphenol | HCID 297382 | — |
| Reactant | 3-Hydroxy-1,2,3,6-tetrahydropyridine, N-BOC protected | HCID 17750131 | — |
| Reactant | Tert-butyl 7-hydroxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate | HCID 67325270 | — |
| Product | Tert-butyl 6-hydroxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate | HCID 68305717 | — |
Reaction Steps
Tert-butyl 6-hydroxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate was synthesized as described for tert-butyl 7-hydroxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate starting N-boc-3-hydroxy-1,2,3,6-tetrahydropyridine and 2-bromo-4-methoxyphenol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765779B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-bfa0669c00b545b0839efe41a04e47ee |
| Source note | uspto-grants-2014_07 |