Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1616906Generated: October 30, 2026

2,6-Dibromophenol → Tert-butyl 8-bromo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate

https://huagongshe.com/reaction/1616906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DibromophenolHCID 11847—
Reactant3-Hydroxy-1,2,3,6-tetrahydropyridine, N-BOC protectedHCID 17750131—
Reactanttert-butyl 7-methoxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylateHCID 67324335—
ProductTert-butyl 8-bromo-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylateHCID 71009066—

Reaction Steps

Prepared as described for tert-butyl 7-methoxy-3,4,4a,9a-tetrahydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate starting from N-boc-3-hydroxy-1,2,3,6-tetrahydropyridine and 2,6-dibromo-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765779B2
Source datasetuspto-grants-2014_07
ORD IDord-725252c3111d4dbf90136072cc262f17
Source noteuspto-grants-2014_07