HCID 67376333, compound → HCID 67379154, compound
Reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]2[C:8]3[C:13](C)([CH3:14])[CH2:12][N:11]([C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:10][C:9]=3[O:23][C:4]=2[CH:3]=1.IC1C=CC2C(C(C)(C)CN)=COC=2C=1.IC1C=CC2C(C(C)C#N)=COC=2C=1>>[C:19]([O:18][C:16]([N:11]1[CH2:12][CH:13]([CH3:14])[C:8]2[C:5]3[CH:6]=[CH:7][C:2]([I:1])=[CH:3][C:4]=3[O:23][C:9]=2[CH2:10]1)=[O:17])([CH3:20])([CH3:21])[CH3:22]Participants
3
Procedure
Synthesized as described for tert-butyl 7-iodo-4,4-dimethyl-3,4-dihydro[1]benzofuro[2,3-c]pyridine-2(1H)-carboxylate using 2-(6-Iodo-benzofuran-3-yl)-propionitrile 2-(6-Iodo-benzofuran-3-yl)-2-methyl-propylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-e3e666d66cbb44ac88c9161453cf3773
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08765779B2
Reaction notes
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