HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenol → 1-(2-Hydroxy-5-chlorophenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenol | HCID 4684 | — |
| Reactant | 1-(4-Hydroxyphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione | HCID 67258169 | — |
| Product | 1-(2-Hydroxy-5-chlorophenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione | HCID 67256147 | — |
Reaction Steps
Compound 34 was prepared from 4-chlorophenol in the same manner of compound 27, and was obtained as white solids (56%). 1H NMR (300 MHz, Methanol-d4): δ 7.75 (d, J=3.0 Hz, 1H), 7.52-7.46 (m, 4H), 7.38 (m, 1H), 7.08 (dd, J=1.8, 8.7 Hz, 1H), 6.88 (d, J=8.7 Hz, 1H). 13C NMR (75 MHz, DMSO-d6): δ 153.70, 152.32, 132.28, 129.63, 128.93, 128.19, 127.12, 126.41, 126.23, 124.62, 123.70, 118.20. HRMS: calcd for C14H10ClN3O3 (MH+) 304.0483. found 304.0487.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765920B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-b0c0a5c964704259b52f949ad12b98bc |
| Source note | uspto-grants-2014_07 |