2-Naphthol → 1-(2-Hydroxynaphtyl)-4-phenyl-1,2,4-triazolidine-3,5-dione

Participants

Role	Name	HCID	Charge
Reactant	2-Naphthol	HCID 8663	—
Reactant	1-(4-Hydroxyphenyl)-4-phenyl-1,2,4-triazolidine-3,5-dione	HCID 67258169	—
Product	1-(2-Hydroxynaphtyl)-4-phenyl-1,2,4-triazolidine-3,5-dione	HCID 67258294	—

Reaction Steps

Compound 35 was prepared from 2-naphthol in the same manner of compound 27, and was obtained as white solids (89%). 1H NMR (300 MHz, DMSO-d6): δ 10.94 (br s, 1H), 7.95 (d, J=9.0 Hz, 1H), 7.89 (d, J=8.1 Hz, 1H), 7.80 (d, J=8.4 Hz, 1H), 7.58-7.50 (m, 5H), 7.44-7.35 (m, 2H), 7.27 (dd, J=2.4, 9.0 Hz, 1H). 13C NMR (75 MHz, DMSO-d6): δ 154.39, 152.93, 152.16, 133.29, 132.99, 132.18, 129.59, 128.77, 128.58, 128.45, 128.29, 126.88, 124.19, 121.90, 119.38, 114.74. HRMS: calcd for C18H13N3O3 (MH+) 320.103. found 320.1032.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08765920B2
Source dataset	uspto-grants-2014_07
ORD ID	ord-54f4ce67f85c46dc994a19cf0819f0bd
Source note	uspto-grants-2014_07