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4-(Pyrrolidin-1-yl)butan-1-ol → 4-(Pyrrolidin-1-yl)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Pyrrolidin-1-yl)butan-1-ol | HCID 13171952 | — |
| 反応物 | 2-(4-((2-Amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetic acid | HCID 68414136 | — |
| 生成物 | 4-(Pyrrolidin-1-yl)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate | HCID 42613681 | — |
反応手順
The title compound was prepared using the product of step (i) (50 mg), 4-(pyrrolidin-1-yl) butan-1-ol (64.2 mg) and the method of example 74 step (iii) to give a tan solid, 9 mg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08765939B2 |
| 出典データセット | uspto-grants-2014_07 |
| ORD ID | ord-b030d783dd6844d6bbf63cdbfde6d875 |
| 出典メモ | uspto-grants-2014_07 |