4-Methyl-5-(2-hydroxyethyl)thiazole → 2-(4-Methylthiazol-5-yl)ethyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxyphenyl)acetate

Participants

Role	Name	HCID	Charge
Reactant	4-Methyl-5-(2-hydroxyethyl)thiazole	HCID 1136	—
Reactant	2-(4-((2-Amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxyphenyl)acetic acid	HCID 68414178	—
Product	2-(4-Methylthiazol-5-yl)ethyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxyphenyl)acetate	HCID 57824828	—

Reaction Steps

The title compound was prepared using the method of example 89 step (vii), using the product of example 89 step (vi) (150 mg) and 2-(4-methylthiazol-5-yl)ethanol (60 mg) to give the title compound as a gum, 10 mg.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08765939B2
Source dataset	uspto-grants-2014_07
ORD ID	ord-866db477bafc49cc9bafb7adaab6cc86
Source note	uspto-grants-2014_07