化工社化工社 化学情報印刷レポート · 研究参考用
4-(Dimethylamino)butan-1-ol → 4-(Dimethylamino)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Dimethylamino)butan-1-ol | HCID 83350 | — |
| 反応物 | 2-(4-((2-Amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetic acid | HCID 68414136 | — |
| 生成物 | 4-(Dimethylamino)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-hydroxyphenyl)acetate | HCID 57824844 | — |
反応手順
The title compound was prepared using product of example 79 step (i) (80 mg) and 4-(dimethylamino)butan-1-ol using the general coupling method of example 74 step (iii). The product was purified by RPHPLC to give the product, 25 mg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08765939B2 |
| 出典データセット | uspto-grants-2014_07 |
| ORD ID | ord-8cfc86100e3348eb866ce21acd8e6255 |
| 出典メモ | uspto-grants-2014_07 |