3-(Methylsulfonyl)phenylboronic acid → HCID 136166989, compound

HRID 1617455Notes

Reaction equation

HRID 1617455 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:8]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9]/[C:10](/[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[N:11]\[OH:12])[CH:5]=[CH:6][CH:7]=1.[CH3:25][S:26]([C:29]1[CH:30]=[C:31](B(O)O)[CH:32]=[CH:33][CH:34]=1)(=[O:28])=[O:27]>>[CH3:25][S:26]([C:29]1[CH:34]=[C:33]([C:2]2[CH:7]=[CH:6][CH:5]=[C:4]([CH:8]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:9]/[C:10](/[C:13]3[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=3)=[N:11]\[OH:12])[CH:3]=2)[CH:32]=[CH:31][CH:30]=1)(=[O:28])=[O:27]

Participants

3

Reactant 2

HCID 27735423-(Methylsulfonyl)phenylboronic acidHCID 136167038HCID 136167038, compound

Product 1

HCID 136166989HCID 136166989, compound

Procedure

In analogy to example 22, from (E)-3-(3-bromo-phenyl)-3-phenyl-1-pyridin-4-yl-propan-1-one oxime (example 12) and (3-methylsulfonylphenyl)boronic acid was prepared the title compound as a white foam, MS (ESI+): m/z=457.2 ([M+H]+).

Sources & evidence

ORD record
ord-eb849bed25584f678962c0fceb71a1e6
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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