4-(Methanesulfonyl)phenylboronic acid → HCID 136167055, compound

HRID 1617456Notes

Reaction equation

HRID 1617456 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:8]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9]/[C:10](/[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[N:11]\[OH:12])[CH:5]=[CH:6][CH:7]=1.[CH3:25][S:26]([C:29]1[CH:34]=[CH:33][C:32](B(O)O)=[CH:31][CH:30]=1)(=[O:28])=[O:27]>>[CH3:25][S:26]([C:29]1[CH:34]=[CH:33][C:32]([C:2]2[CH:7]=[CH:6][CH:5]=[C:4]([CH:8]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:9]/[C:10](/[C:13]3[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=3)=[N:11]\[OH:12])[CH:3]=2)=[CH:31][CH:30]=1)(=[O:28])=[O:27]

Participants

3

Reactant 2

HCID 27343644-(Methanesulfonyl)phenylboronic acidHCID 136167038HCID 136167038, compound

Product 1

HCID 136167055HCID 136167055, compound

Procedure

In analogy to example 22, from (E)-3-(3-bromo-phenyl)-3-phenyl-1-pyridin-4-yl-propan-1-one oxime (example 12) and (4-methylsulfonylphenyl)boronic acid was prepared the title compound as a colorless oil, MS (ESI+): m/z=457.3 ([M+H]+).

Sources & evidence

ORD record
ord-b64c3adc591a488c95ac9fa494bb0eed
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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