4-(Ethylsulphonyl)benzeneboronic acid → HCID 136166886, compound

HRID 1617458Notes

Reaction equation

HRID 1617458 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9]/[C:10](/[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[N:11]\[OH:12])=[CH:4][CH:3]=1.[CH2:25]([S:27]([C:30]1[CH:35]=[CH:34][C:33](B(O)O)=[CH:32][CH:31]=1)(=[O:29])=[O:28])[CH3:26]>>[CH2:25]([S:27]([C:30]1[CH:35]=[CH:34][C:33]([C:2]2[CH:7]=[CH:6][C:5]([CH:8]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:9]/[C:10](/[C:13]3[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=3)=[N:11]\[OH:12])=[CH:4][CH:3]=2)=[CH:32][CH:31]=1)(=[O:28])=[O:29])[CH3:26]

Participants

3

Reactant 2

HCID 27734204-(Ethylsulphonyl)benzeneboronic acidHCID 136167080HCID 136167080, compound

Product 1

HCID 136166886HCID 136166886, compound

Procedure

In analogy to example 22, from (E)-3-(4-bromo-phenyl)-3-phenyl-1-pyridin-4-yl-propan-1-one oxime (example 5) and 4-(ethanesulfonyl)benzeneboronic acid was prepared the title compound as a white foam, MS (ESI+): m/z=471.1 ([M+H]+).

Sources & evidence

ORD record
ord-65d56da3a60d4c279d40f70bb7b2447d
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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