HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-iodo-5-methylpyridine → 1-(2-Fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-iodo-5-methylpyridine | HCID 10060052 | — |
| Reactant | N-Methoxy-N-methyl-3,3-diphenyl-propionamide | HCID 54293842 | — |
| Product | 1-(2-Fluoro-5-methyl-pyridin-4-yl)-3,3-diphenyl-propan-1-one | HCID 67015543 | — |
Reaction Steps
In analogy to example 55, step 2, the title compound was prepared from N-methoxy-N-methyl-3,3-diphenyl-propionamide and 2-fluoro-4-iodo-5-picoline (CAS RN: [153034-94-7]) as a yellow liquid, MS (ESI+): m/z=320.1 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-eaac8e3a5c014ed6aa35ea2ad3f31e3f |
| Source note | uspto-grants-2014_07 |