Hydroxyamine hydrochloride → 2-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-pyridin-4-yl-ethanone oxime

Participants

Role	Name	HCID	Charge
Reactant	Hydroxyamine hydrochloride	HCID 443297	—
Reactant	Sodium Bicarbonate	HCID 516892	—
Reactant	2-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-pyridin-4-yl-ethanone	HCID 67015505	—
Product	2-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-pyridin-4-yl-ethanone oxime	HCID 136359976	—

Reaction Steps

In analogy to example 1, step 2, from 2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-pyridin-4-yl-ethanone and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound containing less than 5% of the Z-isomer as a white solid, MS (ESI+): m/z=([M+H]+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08765730B2
Source dataset	uspto-grants-2014_07
ORD ID	ord-24056e2485cd4bd894b78137a7d016e6
Source note	uspto-grants-2014_07