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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617510Generated: November 1, 2026

(3-Ethoxycarbonylphenyl)boronic acid → 4'-[3-(2-Methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1617510

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Ethoxycarbonylphenyl)boronic acidHCID 3249312—
Reactant3-(4-Bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-oneHCID 66668180—
Product4'-[3-(2-Methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-3-carboxylic acid ethyl esterHCID 66666196—

Reaction Steps

In analogy to example 74, step 6, from 3-(4-bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one (example 74, step 5) and 3-ethoxycarbonylphenylboronic acid was prepared the title compound as a yellow oil, MS (ESI+): m/z=464.22 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-aa8b719c4465430c8a2d24185a5e558e
Source noteuspto-grants-2014_07