Hydroxyamine hydrochloride → 4'-[3-[Hydroxyimino]-3-(2-methyl-pyridin-4-yl)-1-o-tolyl-propyl]-biphenyl-3-carboxylic acid ethyl ester

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Reaction Steps

In analogy to example 74, step 7, from 4′-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-3-carboxylic acid ethyl ester and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (3.4:1) as a white foam, MS (ESI+): m/z=479.2319 ([M+H]+).

Provenance & Evidence