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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617524Generated: November 2, 2026

Hydroxyamine hydrochloride → HCID 136359993, compound

https://huagongshe.com/reaction/1617524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 66666217HCID 66666217—
ProductHCID 136359993HCID 136359993—

Reaction Steps

In analogy to example 74, step 7, from 3-({4′-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carbonyl}-amino)-propionic acid and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (4:1) as a colorless oil, MS (ESI+): m/z=522.2376 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-cc2a68d4fd074f858a78208d4d3958e7
Source noteuspto-grants-2014_07