Hydroxyamine hydrochloride → 5-{3-[3-[Hydroxyimino]-3-(2-methyl-pyridin-4-yl)-1-o-tolyl-propyl]-phenyl}-pyridine-2-carboxylic acid

Participants

Reaction Steps

In analogy to example 74, step 7, from 5-{3-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-phenyl}-pyridine-2-carboxylic acid and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (3:1) as a white solid, MS (ESI+): m/z=452.4 [M+H]+.

Provenance & Evidence