Hydroxyamine hydrochloride → HCID 136360000, compound

Participants

Reaction Steps

In analogy to example 74, step 7, from 3-fluoro-3′-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl ester and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a mixture of E and Z isomers (4.4:1) as a white foam, MS (ESI+): m/z=483.2 ([M+H]+).

Provenance & Evidence