Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-5-fluoro-4-iodopyridine → 3-(4-Bromo-phenyl)-1-(2-chloro-5-fluoro-pyridin-4-yl)-3-o-tolyl-propan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-5-fluoro-4-iodopyridine | HCID 24820495 | — |
| 반응물 | 3-(4-Bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide | HCID 86660949 | — |
| 생성물 | 3-(4-Bromo-phenyl)-1-(2-chloro-5-fluoro-pyridin-4-yl)-3-o-tolyl-propan-1-one | HCID 86660986 | — |
반응 단계
In analogy to example 74, step 5, from 3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 74, step 4) and 2-chloro-5-fluoro-4-iodopyridine (CAS RN: [659731-48-3]) was prepared the title compound as a white solid, MS (ESI−): m/z=430.0013 ([M−H]−, 1Br).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08765730B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-89598e34b1ca497ebdb916558f0c3c74 |
| 출처 메모 | uspto-grants-2014_07 |