2-Fluoro-5-methylpyridine → HCID 67015626, compound

HRID 1617577Notes

Reaction equation

HRID 1617577 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[CH3:22])[CH2:9][C:10](N(OC)C)=[O:11])=[CH:4][CH:3]=1.[F:23][C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][N:25]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[CH3:22])[CH2:9][C:10]([C:29]2[C:24]([F:23])=[N:25][CH:26]=[C:27]([CH3:30])[CH:28]=2)=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27746352-Fluoro-5-methylpyridineHCID 866609493-(4-Bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide

Product 1

HCID 67015626HCID 67015626, compound

Procedure

In analogy to example 74, step 5, from 3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-o-tolyl-propionamide (example 74, step 4) and 2-fluoro-5-methylpyridine (CAS RN: [2369-19-9]) was prepared the title compound as a colorless oil, MS (ESI+): m/z=411 ([M]+, 1Br).

Sources & evidence

ORD record
ord-e7ca8f18799741dd923dbc2f960772e3
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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