Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 86660989, compound

HRID 1617579Notes

Reaction equation

HRID 1617579 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:13]([CH3:16])([CH3:15])[CH3:14])[CH2:9][C:10](O)=[O:11])=[CH:4][CH:3]=1.Cl.[CH3:18][NH:19][O:20][CH3:21]>>[CH3:21][O:20][N:19]([CH3:18])[C:10](=[O:11])[CH2:9][CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1)[C:13]([CH3:16])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 81138Methanamine, N-methoxy-, hydrochloride (1:1)HCID 24260205HCID 24260205, compound

Product 1

HCID 86660989HCID 86660989, compound

Procedure

In analogy to example 74, step 4, from 3-(4-bromo-phenyl)-4,4-dimethyl-pentanoic acid (CAS RN: [1017356-66-9]) and N,O-dimethylhydroxylamine hydrochloride was prepared the title compound as a white solid, MS (ESI+): m/z=328.0895 ([M+H]+, 1Br).

Sources & evidence

ORD record
ord-63dd0f2de44645999cd64c8e36718de7
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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