4-Bromo-2-methylpyridine → HCID 66666136, compound

HRID 1617585Notes

Reaction equation

HRID 1617585 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[C:22]([F:25])([F:24])[F:23])[CH2:9][C:10](N(OC)C)=[O:11])=[CH:4][CH:3]=1.Br[C:27]1[CH:32]=[CH:31][N:30]=[C:29]([CH3:33])[CH:28]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[C:22]([F:23])([F:24])[F:25])[CH2:9][C:10]([C:27]2[CH:32]=[CH:31][N:30]=[C:29]([CH3:33])[CH:28]=2)=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27628354-Bromo-2-methylpyridineHCID 86660992HCID 86660992, compound

Product 1

HCID 66666136HCID 66666136, compound

Procedure

In analogy to example 74, step 5, from 3-(4-bromo-phenyl)-N-methoxy-N-methyl-3-(2-trifluoromethyl-phenyl)-propionamide and 4-bromo-2-methylpyridine was prepared the title compound as a white solid, MS (ESI+): m/z=448.0 ([M+H]+, 1Br).

Sources & evidence

ORD record
ord-2493bec7911a4e8c8d4b3e5ce6692918
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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