1-(6-Methylpyridin-2-yl)piperazine → 9-{4-[4-(6-methyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide

HRID 161759Notes

Reaction equation

HRID 161759 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[n:7]1.[F:14][C:15]([CH2:16][NH:17][C:18](=[O:19])[C:20]1([CH2:33][CH2:34][CH2:35][CH2:36][Br:37])[c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]2-[c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]21)([F:38])[F:39]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([CH2:36][CH2:35][CH2:34][CH2:33][C:20]3([C:18]([NH:17][CH2:16][C:15]([F:14])([F:38])[F:39])=[O:19])[c:21]4[cH:22][cH:23][cH:24][cH:25][c:26]4-[c:27]4[cH:28][cH:29][cH:30][cH:31][c:32]43)[CH2:12][CH2:13]2)[n:7]1

Participants

3

Reactant 2

HCID 27369461-(6-Methylpyridin-2-yl)piperazineHCID 105264379-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide

Product 1

HCID 226401429-{4-[4-(6-methyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide

Sources & evidence

ORD record
ord-05794b22cced4881accbf2db5817cecf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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