4-Bromo-2-methylpyridine → HCID 66667223, compound

HRID 1617593Notes

Reaction equation

HRID 1617593 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=2[CH3:23])[CH2:9][C:10](N(OC)C)=[O:11])=[CH:4][CH:3]=1.Br[C:25]1[CH:30]=[CH:29][N:28]=[C:27]([CH3:31])[CH:26]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=2[CH3:23])[CH2:9][C:10]([C:25]2[CH:30]=[CH:29][N:28]=[C:27]([CH3:31])[CH:26]=2)=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27628354-Bromo-2-methylpyridineHCID 86660998HCID 86660998, compound

Product 1

HCID 66667223HCID 66667223, compound

Procedure

In analogy to example 74, step 5, from 3-(4-bromophenyl)-3-(4-chloro-2-methylphenyl)-N-methoxy-N-methylpropanamide and 4-bromo-2-methylpyridine was prepared the title compound as a light brown solid, MS (ESI+): m/z=430.04 [M+H]+.

Sources & evidence

ORD record
ord-014aa86fa40a4845904899553acddc39
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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