4-Carboxyphenylboronic Acid → HCID 136166827, compound

HRID 1617595Notes

Reaction equation

HRID 1617595 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:20]2[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:21]=2[CH3:27])[CH2:9]/[C:10](/[C:13]2[CH:18]=[CH:17][N:16]=[C:15]([CH3:19])[CH:14]=2)=[N:11]\[OH:12])=[CH:4][CH:3]=1.[C:28]([C:31]1[CH:36]=[CH:35][C:34](B(O)O)=[CH:33][CH:32]=1)([OH:30])=[O:29]>>[Cl:26][C:23]1[CH:24]=[CH:25][C:20]([CH:8]([C:5]2[CH:6]=[CH:7][C:2]([C:34]3[CH:35]=[CH:36][C:31]([C:28]([OH:30])=[O:29])=[CH:32][CH:33]=3)=[CH:3][CH:4]=2)[CH2:9]/[C:10](=[N:11]\[OH:12])/[C:13]2[CH:18]=[CH:17][N:16]=[C:15]([CH3:19])[CH:14]=2)=[C:21]([CH3:27])[CH:22]=1

Participants

3

Reactant 2

HCID 3121834-Carboxyphenylboronic AcidHCID 136167067HCID 136167067, compound

Product 1

HCID 136166827HCID 136166827, compound

Procedure

In analogy to example 74, step 6, from 3-(4-bromophenyl)-3-(4-chloro-2-methylphenyl)-1-(2-methylpyridin-4-yl)propan-1-one oxime (example 138) and 4-carboxyphenylboronic acid was prepared the title compound as a light brown foam, MS (ESI+): m/z=485.162 [M+H]+.

Sources & evidence

ORD record
ord-9a9ff20d088f458d9b25b1b7a0bc0cf2
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

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