Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 86661001, compound

HRID 1617596Notes

Reaction equation

HRID 1617596 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=2[CH3:20])[CH2:9][C:10](O)=[O:11])=[CH:4][CH:3]=1.Cl.[CH3:22][NH:23][O:24][CH3:25]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=2[CH3:20])[CH2:9][C:10]([N:23]([O:24][CH3:25])[CH3:22])=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 81138Methanamine, N-methoxy-, hydrochloride (1:1)HCID 66666174HCID 66666174, compound

Product 1

HCID 86661001HCID 86661001, compound

Procedure

In analogy to example 74, step 4, from 3-(4-bromophenyl)-3-(4-fluoro-2-methylphenyl)-propanoic acid and N,O-dimethylhydroxylamine hydrochloride was prepared the title compound as a colorless oil, MS (ESI+): m/z=382.06 [M+H]+.

Sources & evidence

ORD record
ord-56133eabe58a4920bce13ae18f4b1ef0
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

Loading…