HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-1-cyclopropylmethyl-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromomethylcyclopropane | HCID 81503 | — |
| Reactant | 5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-1-methyl-1H-pyridin-2-one | HCID 66668507 | — |
| Product | 5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-1-cyclopropylmethyl-1H-pyridin-2-one | HCID 66669168 | — |
Reaction Steps
In analogy to example 161, step 1, 5-[3-(4-bromo-phenyl)-3-o-tolyl-propionyl]-1-methyl-1H-pyridin-2-one (example 162, step 3) was reacted with (bromomethyl)cyclopropane in the presence of potassium carbonate to give the title compound as a colorless foam, MS (ESI+): m/z=450.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-fe39c031eb9649238ab7c9bd3e436a6a |
| Source note | uspto-grants-2014_07 |