HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoacetamide → 2-{5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-2-oxo-2H-pyridin-1-yl}-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoacetamide | HCID 3727 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-1-methyl-1H-pyridin-2-one | HCID 66668507 | — |
| Product | 2-{5-[3-(4-Bromo-phenyl)-3-o-tolyl-propionyl]-2-oxo-2H-pyridin-1-yl}-acetamide | HCID 66668241 | — |
Reaction Steps
In analogy to example 161, step 1, 5-[3-(4-bromo-phenyl)-3-o-tolyl-propionyl]-1-methyl-1H-pyridin-2-one (example 162, step 3) was reacted with iodoacetamide in the presence of potassium carbonate to give the title compound as a colorless foam, MS (ESI+): m/z=453.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-391d772297a24f7bbe5dba190276bd1d |
| Source note | uspto-grants-2014_07 |