Potassium Carbonate → 5-[(E)-C-[2-(4-bromophenyl)-2-(2-methylphenyl)ethyl]-N-hydroxycarbonimidoyl]-1-cyclobutylpyridin-2-one

Participants

Reaction Steps

In analogy to example 161, step 1, 5-[3-(4-bromo-phenyl)-3-o-tolyl-propionyl]-1-methyl-1H-pyridin-2-one (example 162, step 3) was reacted with cyclobutylbromide in the presence of potassium carbonate. The product of this reaction was reacted in analogy to example 151, step 3 with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound as a colorless solid, MS (ESI+): m/z=465.2 [M+H]+.

Provenance & Evidence