Hydroxyamine hydrochloride → HCID 58043383, compound

Participants

Reaction Steps

In analogy to example 151, step 3, (1-{4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoyl}-piperidin-4-yl)-acetic acid was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing less than 10% of the corresponding Z isomer as a colorless solid, MS (ESI−): m/z=514.4 [M−H]−.

Provenance & Evidence