Hydroxyamine hydrochloride → HCID 87237017, compound

Participants

Reaction Steps

In analogy to example 151, step 3, 3-{4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoylamino}-propionic acid was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing less than 10% of the corresponding Z isomer as a colorless solid, MS (ESI−): m/z=460.3 [M−H]−.

Provenance & Evidence